1.BACKGROUND & OBJECTIVE: Full-length form of spleen tyrosine kinase [Syk(L)] is a tumor suppressor gene in breast cancer, which may translocate into cell nucleus and act as a transcriptional repressor.
背景与目的:全长型脾脏酪氨酸激酶[full-length form of spleen tyrosine kinase,Syk(L)]在乳腺癌中具有抑癌功能,可移位到细胞核内,作为转录抑制因子调节基因的转录。
2.Alteration of Levels of Cyclic Nucleotide and Analysis of SDS-PAGE in Autologous Transplanted Spleen and Splenic Artery Ligation
Alteration of Levels of Cyclic Nucleotide and Analysis of SDS－PAGE in Autologous Transplanted Spleen And Splenic Artery Ligat
3.At 14d, 21d and 28d the antibody titer of NDV were determined and the relative weight (%BW) of thymus, spleen and bursa were estimated.
测定了14、21、28日龄时各组试验鸡血清中NDV抗体水平及胸腺(thymus) 、脾脏(spleen)和法氏囊(bursa)免疫器官指数;
4.It suggested that the artificial infection of BLS in birds in Nanjing was successful. The gene of big liver and spleen disease virus (BLSV) was amplified from livers of inoculated AA chickens by retrotranscription polymerase chain reaction (RT-PCR). RT-PCR product was cloned into pMD18-T vector and sequenced.
根据已报道的鸡大肝大脾病毒(Big Liver and Spleen Disease Virus，BLSV)基因序列，自行设计和合成了一对引物，应用逆转录多聚酶链式反应(RT-PCR)技术，从人工接种发病的AA肉用种鸡肝脏组织中扩增出片段大小为375bp的病毒基因，将扩增的片段克隆到pMD18-T载体，经酶切鉴定及DNA序列测定，表明扩增片段为BLSV基因。
5.According to the theory of spleen is the origin of the acquired constitution and kidney is the origin of congenital constitution,discussed the basis for establishing the therapeutic principle,relation,difference and apolaction of the Invigorating the Kidney Inferior to Invigorating the Spleen and Invigorating the Spleen Inferior to Invigorating the Kidney,inquired further into the interal relations of spleen and kidney.
从脾为后天之本 ,肾为先天之本的理论出发 ,论证了“补肾不如补脾”和“补脾不如补肾”两说的立论依据、区别、联系及在临证中的运用 ,进一步探讨了脾肾两脏之间的内在联系
6.As lower birthweight guineapig to be an animal model, the auther studied the relationship between the kidney-spleen and the contents of endocrine hormone close to the kidney-spleen such as a-drenocorticotropin (ACTH) , cortisol growth hormone and gastrin, and showed the pharmacological action of therapy of tonifying the kidney and invigorating the spleen on regulating the contents of correlative hormone of sick infant and improving them to grow acceleratly.
以出生低体重豚鼠作为胎怯动物模型,研究与“肾”、“脾”关系密切的血清促肾上腺皮质激素(ACTH)、皮质醇、生长激素、胃泌素等内分泌激素水平的关系,显示了补肾健脾法调整胎怯患儿有关激素水平、促进患儿加速生长的药理作用。
7.2. Compared to the control group, the SOD, GSH-PX and T-AOC in the blood serum and the brain cortex were significantly reduced in the spleen Qi deficiency group, the spleen Yang deficiency group and the spleen Yin deficiency group(P
2、与正常对照组相比，脾气虚模型组大鼠血清和脑皮质中SOD、6SH-Px、总抗氧化能力显著降低，且与正常组比较P＜0.05，脾阴虚证、脾阳虚证的SOD、GSH-Px、总抗氧化能力明显降低，且脾阳虚证比脾阴虚证降低的更明显。
8.S180 mice were used to evaluate the antitumor activities in vivo of EERC (Cytoxan as positive drug). LD50, tumor inhibition rate, indices of thymus and spleen, multiplication of spleen lymphocyte (MTT assay), IgA, IgG, IgM and apoptosis rate of spleen lymphocyte were detected, respectively.
用 S180荷瘤鼠体内实验模型进行松节藻醇提取物的抗肿瘤评价(环磷酰胺为阳性对照药物),分别测定 LD50、抑瘤率、胸腺指数、脾指数、脾淋巴细胞增殖活性(MTT 法)、免疫球蛋白 IgA、IgG、IgM 和脾细胞凋亡率等指标,并应用软件 SPSS 进行数据处理。
9.The results showed that the proliferative response and number of T cells in thymus and spleen, the proliferative response of B cells and number of IgG +,IgM +,IgA + antibody producing cells in Bursa of Fabricicus and spleen and the inductive activity of IL 2 and IFN in thymus and spleen of chicken infected with REV were decreased.
结果发现 ,雏鸡感染 REV后 ,胸腺和脾脏 T细胞增殖反应及数量、法氏囊和脾脏 B细胞增殖反应和 Ig G+、Ig M+、Ig A+抗体生成细胞数量均明显低于未感染对照雏鸡 ;
10.Measuring the T lymphocyte subset changes in spleen and thymus after TCV.Result TCV may induce the rising of percentage of CD8 + T lymphocyte subset in spleen and CD4 + CD8 + simple-positive T lymphocyte in thymus,may induce the decreasing of percentage of IL-2R + T lymphocyte and the decreasing of CD4 +/CD8 + rate in spleen.
结果 TCV可以诱导宿主脾脏 CD8+ T细胞百分比升高、CD4+ / CD8+比值和 IL- 2 R+细胞下降 ,以及胸腺 CD4+、CD8+单阳性细胞百分比升高。
