1.The antitumor effects of hematoporphyrin derivative (HpD)activated by ultrasound (US)was studied on Sarcoma180(S180)and Ehrlich ascites tumor(EAT)cells through scanning electronic microscope.
利用频率为2MHz,强度为0.9W/cm2的超声(Ultrasound,US)激活血卟啉(Hematoporphyrinderivatives,HpD)对在体的腹水型艾氏腹水瘤细胞(EhrlichAscitesTumor,EAT)和S180(Sarcoma180,S180)细胞进行抑癌作用研究。
2.OBJECTIVE: To study the clinicopathological characteristics and immunohistochemistry phenotype of endometrial stromal sarcoma (ESS), and their clinical significance for the differential diagnosis between ESS and highly cellular leiomyoma (HCL).
目的:探讨子宫内膜间质肉瘤(endometrial stromal sarcoma,ESS)的临床病理及免疫组织化学特点及其在鉴别诊断中的意义。
3.Objective To study the effects of 20(S)-ginsenoside Rg_3(SPG-Rg_3) on growth of sarcoma 180 and life of mice with sarcoma 180. Methods In vitro,stain exclusion experiment was used to observe the effect of SPG-Rg_3 on sarcoma 180 cells.
目的:探讨20(S)-人参皂苷Rg3(SPG-Rg3)与化疗药物联合应用对S180肉瘤生长以及荷瘤小鼠生命延长期的影响。 方法:体外通过染料排斥实验观察SPG-Rg3抗肿瘤细胞生长的作用。
4.Methods Membrane fluidity of sarcoma cells and fluorescence in tensities of intracellular free calcium concentration [Ca 2+]i in culture d mice S 180 sarcoma cells were measured by adherent cell analysis and sort ing cytometer (ACAS 570) after hyperthmia (43 ℃, 60 min) and compared with the control group.
方法 对体外培养的小鼠S180 肉瘤细胞进行高温 (4 3℃、60min)处理后 ,利用激光粘附式细胞仪测定肿瘤 [Ca2 + ]i的荧光强度及膜脂扩散系数 ,并观察细胞的形态学变化。
5.Conclusion SPG-Rg_3 can inhibite the growth of sarcoma 180 and prolong the life of mice with sarcoma 180.Foremore,SPG-Rg_3 can reinforce the inhibitory effects of CTX and 5-FU on tumor growth.
结论:SPG-Rg3可明显抑制肿瘤的生长,延长荷瘤小鼠的生存期,且SPG-Rg3可以提高CTX和5-FU的抗肿瘤作用,有一定的协同增效作用。
6.Local recurrence occurred frequently in uterine sarcoma(10/16)and pelvic lymphadenopathy in endometrial stromal sarcoma(5/6)and maglinant mixed mullerian tumors(3/5).
复发部位与病理类型有关，局部复发以平滑肌肉瘤多见，占10／16，盆腔淋巴结复发以子宫内膜间质肉瘤及恶性苗勒氏混合瘤多见，分别为5／6及3／5（P＜0?01）。
7.Methods:Thirty one cases with uterine sarcoma were analyzed retrospectively, among which there were 14 cases with leiomyosarcoma(45.16%), 7 with malignant endometrial interstitialsarcomas (22.58%),7 with malignant Mullerian mixed tumor(22.58%),3 with sarcoma botryoides (9.68%).
方法回顾性分析该院收治的子宫肉瘤患者31例的临床资料,其中子宫平滑肌肉瘤14例(45.16%),子宫内膜间质肉瘤7例(22.58%),子宫恶性苗勒管混合瘤7例(22.58%),子宫(颈)葡萄状肉瘤3例(9.68%)。
8.In order to study the enhancement of immune functions and autologous tumor-killing (ATX) activity by kappa-selenocarrageenan (KSC) in mice bearing sarcoma 180, the effects of KSC and/or Cyclophosphamide (Cy) on natural killer(NK) activity, lymphokine activated killer(LAK) activity, the production of interleukin-2 (IL-2), ATK activity and the growth of sarcoma 180 (S180) were observed.
本文研究了硒酸酯多糖(KSC)对荷S180肉瘤小鼠NK细胞活性、LAK细胞活性、IL-2分泌能力和自身肿瘤杀伤活性(ATK)的影响及抑癌效应.
9.The possibility of postirradiation sarcoma after radiation therapy should not be a major factor influencing treatment decision in the patient with breast cancer.
由于放射治疗术后引发肉瘤之机率甚低，因此不应列入乳癌病人接受放射治疗与否之主要参考因素。
10.The sensitizing effects on photooxidation of NADPH in deuterium oxide and photodynamic effects on sarcoma 180 in mice of the chlorins synthesized and their parent porphyrins were compared with those of HpD.
以血卟啉衍生物(HpD)为阳性对照测定了所合成卟啉及其还原所得相应二氢卟啉对还原辅酶Ⅱ (NADPH)在重水中光氧化作用的敏化效应和对小鼠肉瘤 180的光动力损伤作用。
