1.Objective: This study was undertaken to investigate the reasons on placenta dysfunction of intrahepatic cholestasis of pregnancy (ICP). This kind of dysfunction may be caused by the changes of placenta ultrastructure, cell apoptosis in placenta, and over expression of control gene on placenta with ICP.
通过研究妊娠肝内胆汁淤积症(Intrahepatic cholestasis of pregnancy ICP)胎盘超微结构的变化和胎盘细胞凋亡程度及细胞凋亡调控基因对胎盘细胞凋亡的影响来了解妊娠肝内胆汁淤积症胎盘功能减退的原因。
2.Methods The data of 13 cases of placenta previa and its embed in 98 cases of PP were analyzed in pregnant weeks, age, pregnant times, placenta location, bleeding and apgar score from 1995 to 2002. Results The occurrence of placenta previe rate was 1.6% and combined its embed rate was 13.2%.
方法 对我院 1 995 -0 1～ 2 0 0 2-1 2间分娩的 60 5 6例产妇中 ,98例前置胎盘和其中 1 3例合并胎盘植入患者的孕周 ,胎盘位置、产妇年龄、妊娠次数、产后出血量及新生儿Apgar评分等指标进行统计分析。
3.Objective:To explore the effect on bile transport in the placenta of intrahepatic cholestasis of pregnancy(ICP)by detecting the expression of farnesoid X receptor(FXR) and MDR3mRNA in placenta and examination the effects of Chenodeoxycholic acid(CDCA)or Ethinylestradiol on the expression of MDR3 and FXRmRNA in placenta.
目的:本研究通过检测法尼醇受体(Farnesoid X receptor,FXR)、多药耐药基因(MDR3)在胎盘上的表达,以及在雌激素、鹅脱氧胆酸、熊脱氧胆酸作用下两者的变化,从而了解FXR的配体—胆酸在胎盘组织中如何调节FXR及MDR3的表达以及雌激素对FXR和MDR3表达的影响,从而明确FXR在胎盘胆汁酸转运的作用机制。
4.Among all of the 40 patients,90.25% had an abnormal position of fetus,42.5% had a deformed and enlarged placenta,15% appeared local premature in placenta and 77.5% had a caesarean operation.
胎位异常占 90 .2 5 % ,胎盘变形、增大、增厚占 42 .5 % ,胎盘局部早熟样表现占 15 % ,剖宫产率占 77.5 %。
5.The expression of neural and hematopoietic markers in placenta tissue and cultured human placenta derived adherent cells(hPDACs) and their correlation in embryonic development were investigated in this paper.
为探讨人胎盘组织在造血中的作用以及研究造血和神经标志物在胎盘中的表达和在胚胎发育中的相关性,用免疫组织化学法对人胎盘组织和体外培养的胎盘组织中的贴壁细胞进行染色,观察其造血因子和神经标志物的表达。
6.PlaEssence is a unique placenta essence gel formulated using natural placenta protein specially blended with Phyto Collagen, Royal Jelly and Rosewater.
金思黛尔胎盘精华素??ㄊ且恢质褂锰烊惶ヅ痰鞍子胫参锝涸?省⒎浠式?约懊倒逅???乇鸬髦贫?桑?哂卸捞嘏浞降幕し舨?贰
7.Results Compared with normal pregnancy placenta,393 genes(4.79%) in PIH placenta were expressed differentily. Of them,197 genes had low expression,and 196 high expression.
结果与正常妊娠胎盘表达的基因相比,PIH胎盘组织中有393条(4.79%)的基因表达发生了变化,其中197条基因在PIH时表达量降低,而196条基因在妊娠期高血压疾病时表达量增高。
8.The associated factors of postpartum haemorrhage in placenta previa were history of multiple abortions (more than twice) , previous cesa rean section, elder age, type of placenta previa, no prenatal check, prenatal bleeding and other complications.
( 2 )与前置胎盘产后出血量有关的因素有高龄产妇、2次以上流产史、剖宫产史、前壁的前置胎盘、完全性前置胎盘、有产前出血史、无产前检查、存在妊娠合并症或并发症 ;
9.There were 24 cases of emergency peripartum hysterectomy among 7,617 cases of deliveries during 17 years, accounting for 3.15‰. Among them, there were11 cases of placental adherence including 7 cases of placenta accrete and 5 cases of placenta abruption, 6 cases of inertia uteri and 2 cases of uterine rupture.
结果:17年间在本院分娩的7 617例中,24例行急诊产科子宫切除术,发生率3.15％o,其中胎盘粘连11例(胎盘植入7例),胎盘早剥5例,子宫收缩乏力6例,子宫破裂2例。
10.Conclusion Lower segment longitudinal caesarean section in placenta praevia not only shows less bleeding during operation and lower rate of postpartum haemorrhage, but also avoids using gauzes to stop bleeding and causes lower rate of hysterectomy after caesarean section, so it can be the first choice when determining the style of section in placenta praevia.
结论 前置胎盘行子宫下段纵切口剖宫产术不仅可以减少术中出血量、产后出血率 ,而且避免子宫切口撕裂、宫腔填纱条和剖宫产术时子宫切除率也明显减少 ,是前置胎盘剖宫产结束妊娠的首选切口。
