1.Objective:The purpose of this study is to investigate the expression of intercellular adhesion molecule-1(ICAM-1) in the blood-brain barrier (BBB) and soluble intercellular adhesion molecule-1(sICAM-1); leukocyte infiltration and brain edema and study the effects of hypothermia therapy on them . Then to discuss the mechanism of protection of hypothermia therapy to blood-brain barrier following traumatic brain injury in rats.
目的:本研究观察大鼠颅脑外伤后血脑屏障中细胞间黏附分子-1(intercellular adhesion molecule-1,ICAM-1)及血清中可溶性细胞间黏附分子-1(soluble intercellular adhesion molecule-1,sICAM-1)的表达和白细胞浸润及其应用亚低温对它们的影响情况,探讨早期应用亚低温治疗对大鼠颅脑损伤后血脑屏障的保护机制。
2.Objective To characterize the effect of hyperbaric oxygenation(HBO) therapy on the levels of serum soluble intercellular adhesion molecule-l(sICAM-l), soluble vascular cell adhesion molecule-1(sVCAM-l) in patients with acute cerebral infarction(ACI) and their clinical significance.
目的 探讨高压氧治疗对急性脑梗死患者血清可溶性细胞间粘附分子-1(soluble intercellular adhesion molecule-1,sICAM-1)、可溶性血管细胞粘附分子-1(soluble vascular cell adhesion molecule-1,sVCAM-1)含量的影响及临床意义。
3.At 437 K, the CVT/SCT rate constants were 6.72×10~ -19 , 8.01×10~ -18 and 8.82×10~ -20 cm~ 3 /(molecule·s), which were in agreement with the experimental values 3.31×10~ -19 , 1.05×10~ -18 and 8.33×10~ -20 cm~ 3 /(molecule·s).
在437K时,kCVT/SCT分别为6.72×10-19,8.01×10-18和8.82×10-20cm3/(molecule.s).
4.In this article we calculate the curves of the ground state 2∑3s, the excited state 2Π3p of the molecule HeNa and the states of 1Π2p, 3∑3s and 1∑3s of the cation HeNa+ by using the db initio Molecule-UHF program. Furthermore, we calculate the Franck-Condon factors of the excitation from state to state by using the program made by us.
利用从头算Molecule-UHF程序计算得到HeNa分子的基态~2∑3s及激发态~2∏3p和HeNa~+的~1∑2p、~3∑3s及~t∑3s态的势能曲线,并在此基础上利用自编的程序计算了态-态间光谱跃迁的Franck-Condon因子.
5.Epithelial cell adhesion molecule (EP-CAM), also called 17-1 A, ESA, EGP40, is a 40KDa epithelial transmembrane glycoprotein, encoded by the GA733-2 gene, to function as a homophilic cell adhesion molecule, in a Ca2+ - independent manner in benign and malignant epithelial cells.
EP-CAM(epithelial cell adhesion molecule)，也称为17-A，ESA，EGP40，是一种由GA-733-2基因编码的分子量为40KDa的跨膜糖蛋白，作为嗜同种的钙非依赖性的上皮细胞间粘附分子在上皮癌变过程中发挥着作用。
6.Reserch has shown that cytokine and adhesion molecule such as nuclear factor kappa B (NF-κB ) , interelluar adhesion molecule-1 (ICAM-1) , tumor necrosis factor α ( TNF-α) and interleukin-6 ( IL-6) played important roles in occurrence and development of liver inflammation and liver fibrosis,but the reserch about the influence of NF-κB and its regulatory products to AIH was rare relatively.
研究表明，核因子-κB(nuclear factor kappa B，NF-κB)、细胞间粘附分子-1(interelluar adhesion molecule-1，ICAM-1)、肿瘤坏死因子-α(tumor necrosis factor α，TNF-α)及白细胞介素-6(interleukin-6，IL-6)等炎性细胞因子、粘附分子在肝脏炎症、肝纤维化的发生及发展过程中起重要作用。
7.IN SITU IMMUNOHISTOCHEMISTRY STUDY OF INTERCELLULAR ADHESION MOLECULE-1(ICAM-1 ) IN CHRONIC COLITIS AND COLON CANCER
IN SITU IMMUNOHISTOCHEMISTRY STUDY OF INTERCELLULAR ADHESION MOLECULE－1（ICAM－1） IN CHRONIC COLITIS AND COLON CANCER
8.At 2000K,the total rate constants of the two reactions were 6.32×10-12 and 8.41×10-12 cm3·molecule-1·s-1,the branching ratios of the Abstraction of hrdrogen reactions were 91.8% and 79.4%.
2000 K时其总速率常数分别为6.32×10-12和8.41×10-12cm3.molecule-1.s-1,抽氢反应分支比分别为91.8%和79.4%。
9.It is generally acknowledged that AM plays an important role in renal graft rejection, and the functions of Leukocyte function-associated antigen-1(LFA-1) and Intercellular adhesion molecule-1(ICAM-1) are especially important.
现已公认它在同种异体肾移植排斥反应中具有重要作用，其中淋巴细胞功能相关抗原-1（Leukocyte function-associated antigen-1，LFA-1）和细胞间粘附分子-1（Intercellular adhesion molecule-1，ICAM-1）的作用尤为重要。
10.Great attention is paid to NF-kB in the allergy disease pathogenesis and the treatment. Intercellular adhesion molecule-1 (ICAM-1) adjusted by NF-κB is an important biological active agents which plays a key role on the emergence and development of local inflammation.
细胞间粘附分子-1(intercellular adhesion molecule-1，ICAM-1)在局部炎症的发生和形成中具有重要的作用，是一种重要的生物活性物质，其基因表达受NF-κB的调节。
