1.It is generally acknowledged that AM plays an important role in renal graft rejection, and the functions of Leukocyte function-associated antigen-1(LFA-1) and Intercellular adhesion molecule-1(ICAM-1) are especially important.
现已公认它在同种异体肾移植排斥反应中具有重要作用,其中淋巴细胞功能相关抗原-1(Leukocyte function-associated antigen-1,LFA-1)和细胞间粘附分子-1(Intercellular adhesion molecule-1,ICAM-1)的作用尤为重要。
2.Objective:To study the effects of intercellular adhesion molecule 1 (ICAM 1) and human leukocyte antigen (HAL DR) on the immunopathologic process of uveitis.
目的:研究细胞间粘附分子?1(intellular adhesion m olecule?1, I C A M ?1)和人体组织相关抗原(hum an leukocyte antigen, H L A? D R)在葡萄膜炎免疫反应中的作用。
3.Methods By using the DXC 300A erythrocyte deformability apparatus, platelet and thrombus adhesion dual purpose apparatus and enzyme linked immunosorbent assay (ELISA) methods, the changes of leukocyte deformability (LD),leukocyte adhesion function(LAF),leukocyte CD 18 expression and serum soluble intercellular adhesion molecule 1 (sICAM 1) were measured in patients with psoriasis before and after treatment with PSS.
2方法 采用 DXC- 30 0 A型核孔滤膜红细胞变形能力测定仪、体外血栓血小板黏附两用仪及 EL ISA法 ,检测了 PSS治疗前后银屑病病人白细胞变形能力 (L D)及白细胞黏附功能 (L AF) ,白细胞 CD1 8表达及血清可溶性细胞间黏附分子 - 1(s ICAM- 1)含量的变化。
4.The levels of leukocyte count, neutrophil number, leukocyte adhesiveness, leukocyte releasing oxygen free radical (O - 2· ) after phagocytosing bacteria and serum lipid peroxide MDA were determined in the peripheral blood of 40 patients with acute head injury within 48 hours and 22 normal adults. These levels of patients were significantly higher than those of the controls ( P <0.05), and increased with the severity of craniocerebral injury elevation.
40例急性颅脑损伤患者,伤后48h内检测外周血中白细胞粘附性、吞噬后释放O-2·的水平,MDA,白细胞计数和中性粒细胞数。
5.The Changes of Leukocyte Deformability, Leukocyte Adhesion Function and Expression of Cell Adhesion Molecules in Patients with Coronary Heart Disease
冠心病患者白细胞变形能力和粘附功能及细胞粘附分子表达的变化
6.The results showed that the leukocyte adhesion rate (LAR)and leukocyte filtration index (IF) in diabetic patients were higher than those in normal controls (P
结果显示,NIDDM病人白细胞粘附率(LAR)和白细胞滤过指数(IF)明显增高,与对照组相比差异有显著性(P<0.001),且有血管病变者变化比无血管病变者更明显。
7.Leukocyte was apheresised by COBE Spectra,the counts of reinfused leukocyte (CD 3 + cell) were 1.71×1.0 7/kg[ (0.6~3.4)×10 7/kg],and before DLI,discontinued immunosuppressant.
预处理方案用去髓性和非去髓性两种。 供体白细胞采用 COBE,Spectra血细胞分离机 ,回输的细胞数 (CD3 +)细胞为 (0 .6~ 3.4)× 10 7/ kg,平均细胞数 1.7× 10 7/ kg,DL I前停用免疫抑制剂。
8.Study on changes of peripheral blood leukocyte self-activation and the expression of the CD11b adhesive molecule in leukocyte in patients with hypercholesterolemia
白细胞自发活化与粘附分子CD11b在高胆固醇血症中的应用
9.In nephritic ratst, acute decrements in glo-merular ultrafiltration coefficient (Kf), glomerular filtration rate(GFR) and renal blood flow (RBF) were associated with increments in glomerular leukocyte counts and in the glomerular synthesis of TXB-2 and LTB-4. Leukocyte depletion eliminated the enhanced synthesis of TXB-2 and LTB-4,blocked the decrements in GFR and RBF.
在肾炎鼠,肾小球超滤系数(Kf)、肾小球滤过率(GFR)及肾血流量(RBF)的急性降低伴有肾小球白细胞计数的升高及肾小球TXB_2、LTB_4的合成增多。 白细胞除去可抑制TXB_2及LTB_4的合成并完全防止GFR及RBF的降低。
10.Plasma levels of interleukin-6(IL-6), tumor necrosis factor-alpha(TNF-a), C-reactive protein(CRP), cortisol(CORT), blood glucose(BG), leukocyte differential count(LDC) and body temperature(BT) were measured before and at 4 hours, 24 hours, 48 hours and 72 hours after operation, and to compare the degrees of the related stress responses.
分别在术前、术后4h、术后24h、术后48h及术后72h测量血浆白介素-6(IL-6)、肿瘤坏死因子-a(TNF-a)、C-反应蛋白(CRP)、皮质醇(CORT)、血糖(BG)、白细胞计数(LDC)及体温(BT)的变化,比较它们应激反应程度的不同。