1.It owns efficacy to inhibit thrombosis, prevent myocardial infarction and cerebral infarction, reduce blood lipoid and blood pressure, inhibit hemorrhagic apoplexy, inhibit the occurrence and metastasis of cancer, increase intelligence, protect eyesight and prevent premature senility.
它能够有效地抑制血栓性病症，预防心肌梗塞和脑梗塞，降低血脂、降低血压，抑制出血性中风，抑制癌症的发生和转移，具有增长智力、保护视力、延缓衰老等功效。
2.EGCG was reported to inhibit leukocyte migration in response to chemokines such as IL-8, CINC and MIP-2, to trap reactive oxygen species, to inhibit neutrophil degranulation and inhibit inflammatory mediator release.
EGCG的抗炎作用涉及多个环节，包括抑制趋化因子(如白介素-8(IL-8)、细胞因子诱导的中性粒细胞趋化因子-1(CINC-1)、巨噬细胞炎性蛋白-2(MIP-2)等)诱导的白细胞的定向迁移、清除氧自由基、抑制嗜中性粒细胞脱颗粒及炎性介质的释放等。
3.[Conclusion] Changan capsule can inhibit the synthesis of IgG, clear CIC, inhibit the yields of TNF_α,and regulate the level of IL_2.
[结论]肠安胶囊能够抑制IgG合成 ,清除CIC ,抑制TNF -α产生 ,调控IL -2水平
4.Conclusion: The extract of Angelica sinensis can inhibit the metastasis of of B16-BL6 metastatic mouse melanoma cells and its mechanism is maybe that Angelica sinensis can inhibit the B16-BL6 cells adhering to the ECM and reduce the migration of B16-BL6 cells.
结论:当归提取液能够抑制黑色素瘤高转移细胞株B16-BL6的转移,作用可能与其能够抑制B16-BL6细胞外基质的粘附以及降低B16-BL6的运动能力有关。
5.The results indicated a typical LTD was induced after HFS in control group, superfusion of 20mM ethanol could facilitate the induction of corticostriatal LTD slightly, 40mM ethanol could inhibit the induction of corticostriatal LTD slightly, whereas 60mM and 80mM ethanol could significantly inhibit it in which 60mM ethanol had the strongest inhibitory effect.
研究结果发现:对照组给予强直刺激后诱导出明显的LTD，20蒯酒精可以轻微增强LTD的诱导，4 OmM酒精可以轻微抑制LTD的诱导，6OmM和80mM酒精可明显抑制LTD的诱导，在一定酒精浓度范围内呈现量效关系，其中以60蒯酒精的作用最强。
6.Conclusion ⑴CDDP can inhibit the expression of survivin gene of SGC-7910, HO-8910 and HO-8910pm cell line, so we suggested that CDDP may inhibit cancer by decreasing the expression of survivin gene. ⑵In Hep-2、PC-2 cell lines, survivin gene is not the target of CDDP on anti-cancer function.
结论顺铂可能是通过抑制Survivin基因诱导SGC-7910、HO-8910、HO-8910PM细胞凋亡而发挥其抗肿瘤功效,而对Hep-2、PC-2细胞系Survivin基因的表达没有明显作用。
7.Conclusion Exogenous PTEN can block ASPC-1 cell cycle at the G2/M phase, enhance the cell apoptosis induced by hypoxia, inhibit the expression of VEGF and EGFR proteins under hypoxic condition, and inhibit the proliferation and growth of ASPC-1 cells.
结论外源性PTEN使ASPC-1细胞阻滞在G2／M 期,增强乏氧诱导细胞的凋亡,抑制乏氧诱导VEGF、EGFR表达的增加,抑制肿瘤细胞的增殖。
8.The mutant R 87 L APIB lost about half activity towards trypsin but could inhibit one molecule of chymotrypsin as the wide type APIA did, indicating that Leu 87 was the reactive site towards trypsin but could inhibit one molecule of of APIA for inhibiting chymotrypsin.
经过测定 ,两个突变体K44P R87P APIB和K44P R76P APIB对胰蛋白酶的抑制常数Ki 分别是 0 .39nmol/L和 0 .4 7nmol/L。 突变体R87L APIB(APIA中 87位是Leu)丧失了接近一半的胰蛋白酶抑制活力 ,但同时对胰凝乳蛋白酶的抑制活性由原来?
9.Moreover, lemon has a better ability to scavenge H_2O_2,ONOO~· and DPPH~· than that of basil. Basil and lemon could effectively inhibit lipid peroxidation and they could obviously inhibit and delay DNA damage caused by ()~·OH, acting as mixing-type antioxidants.
罗勒和香柠檬也能有效清除·OH、H2O2、ONOO·和DPPH·,两者相比,香柠檬除对·OH的清除作用弱于罗勒外,清除以上各种自由基的能力均强于罗勒。
10.The results also indicated that basil, lemon and rose could dose-dependently increase the activities of SOD、 CAT and the level of GSH , inhibit the production of lipid peroxidation and (ONOO)~- in the EC and SMC or in the medium of the two while cultured bovine aortic EC and SMC were damaged by H_2O_2. Basil, lemon and rose can also inhibit apotosis in EC and SMC.
也可剂量依赖性地提高H_2O_2胁迫下的EC和SMC内源性SOD、CAT活性及GSH水平,抑制细胞内外的ONOO~-和MDA的产生。 并可减少氧化胁迫下EC和SMC细胞凋亡的数目。
