1.The use of antibody-enzyme conjugates directed at tumor-associated antigens to achieve site-specific activation of prodrugs to potent cytotoxic species, termed antibody-directed enzyme prodrug therapy (ADEPT) has attracted considerable interest since the concept was first described in 1987. ADEPE may improve both the efficiency and the specificity of cytotoxic drugs to achieve selective targeting with minimized host organ toxicity.
1987年提出的抗体导向酶—前药疗法(antibody-directed enzyme prodrug therapy,ADEPT)即抗体与前药的专一性活化酶交联，并将其特异性结合于肿瘤部位，使前药可以区域特异性地在肿瘤组织内转化为细胞毒分子，可以提高毒性药物的特异性和疗效，同时减少毒副作用。
2.Angiotensin converting enzyme(ACE), same as angiotensinogen (AO), renin, angiotensin I (Ang I) and angiotensin II (Ang II), is a main composition in renin-angiotensin system which hydrolyze the Ang I and bradykinin (BK). Many of angiotensin converting enzyme inhibitors (ACEI) were made success in clinic of control hypertension which made it clear that ACE may take important effect on regulation of blood pressure and genesis of hypertension.
同血管紧张素原(angiotensinogen，AO)、肾素、血管紧张素Ⅰ(angiotensin Ⅰ，Ang Ⅰ)和血管紧张素Ⅱ(angiotensin Ⅱ，Ang Ⅱ)一样，、血管紧张素转换酶(angiotensin converting enzyme，ACE)是肾素-血管紧张素系统中重要的组成成员，在Ang Ⅱ形成和缓激肽(bradykinin，BK)降解过程中发挥主要作用，并参与机体血压和水电解质的平衡调节。
3.Recent researches have proven that angiotensin converting enzyme inhibitors (ACEI) can lessen the renal injury in diabetes by decreasing the level of Ang Ⅱ .
血管紧张素转换酶抑制剂(angiotensin-converting enzyme inhibitor，ACEI)通过降低血管紧张素Ⅱ(Ang Ⅱ)含量，可减轻糖尿病的肾损伤；
4.The present study was undertaken to evaluate the levels of MIF in plasma and PF of women with EM by enzyme linked immune sorbent assay (ELISA) , to examine the correlation between MIF levels and the stage of the disease and the phase of menstrual cycle, and to determin the role of MIF in promoting the disease.
本研究用酶联免疫吸附法(enzyme linked immune sorbent assay，ELISA)第一次同时测定了EM患者血浆和PF中MIF的水平，并分析MIF水平与疾病的分期和月经周期之间的关系，探讨MIF在EM发病过程中的作用。
5.Enzyme-linked immunosorbent assay (ELISA) and fluorescent bead immunoassay (FBI) were used to detect the concentration of rhLTα-Da in blood and urine.
分别采用酶联免疫吸附测定法(enzyme-linkedimmunosorbentassay,ELISA)和荧光磁珠免疫分析法(fluorescencebeadimmunoassay,FBI)测定患者给药后血清和尿液中rhLTα-Da浓度。
6.Fasting blood samples were obtained, plasma ghrelin、serum IGF-I concentration were determined by enzyme immunoassay (EIA) and serum leptin、insulin levels were determined by radioimmunoassay (RIA).
晨起空腹留取血样本，酶免疫分析法（enzyme immunoassay, EIA）测定ghrelin、IGF-I的浓度，放射免疫分析法（radioimmunoassay, RIA）测定血清瘦素、胰岛素的含量。
7.Methods: The patients proved to have malignant tumors pathologically. Th1 type(IL-2、IFN-γ)and Th2 type (IL-4、IL-10 )cytokines of these patients serum were detected by enzyme-linked immunosorbant assays (ELISA) 2 days before operation,1 week before and after each NDV-ATV inoculation respectively.
方法：经组织学检查确诊为恶性肿瘤的患者，于手术前2天，NDV-ATV治疗前1周及每次接种后1周，ELISA(Enzyme-Linked Immunosorbant Assays)方法检测外周血血清中Th1类(IL-2、IFN-γ)和Th2类(IL-4、IL-10)细胞因子浓度；
8.Antibody-directed enzyme prodrug therapy (ADEPT) is one of the noticeable new progresses in the research of antibody-directed treatment for tumor in recent years.
抗体导向酶-前体药物疗法(antibody-directed enzyme prodrugtherapy,ADEPT)是近年来肿瘤抗体导向治疗研究中一项引人注目的新进展。
9.Enzyme-linked immunosorbent assay (ELISA) was developed for analysing oxytetrocycline(OTC) from the bee products using the anti-OTC antibody.
本研究通过制备土霉素(oxytetracycline, OTC)的特异性抗体,建立了蜂产品中土霉素残留的酶联免疫吸附分析法(enzyme-linked immunosorbent assay, ELISA)。 具体包括以下四个方面的内容:
10.A specific, sensitive, and simple competitive enzyme immunoassay for the measurement of human apolipoprotein Cn(apo CⅡ)was developed.
本文介绍一种特异、灵敏、简便人血清载脂蛋白CⅡ(apoCⅡ)竞争性酶兔疫测定法(Competitive Enzyme Immunoassay,CEIA)。
