1.Results Cleft lip(CL):931cases (19.57%), Cleft lip with palate(CL + P):2743cases (57.65%), Cleft palate only(CPO):1084 cases (22.78%).
结果 单纯唇裂(cleft lip CL)931例(19.57%),唇裂伴腭裂(cleft lip with palate CL+P)2743例(57.65%),单纯腭裂(cleft palate only CPO)1084例(22.78%)。
2.Objective: Nonsyndromic CLP is composed of two separate entities: cleft lip and palate (CL±P) and cleft palate only (CPO). Cleft lip (CL) with or without cleft palate (CP; CL/P) ranks among the most common birth defects in humans. Our understanding of aetiology and pathogenesis of these birth defects, particularly the non-syndromic variants, remains relatively poor.
背景和目的：非综合征性唇裂伴或不伴腭裂(Nonsyndromic cleft of the lip and／or palate，NCL／P)是常见的出生缺陷，是一种多基因易感性疾病，有着复杂的遗传特点，目前研究认为非综合征唇腭裂的发生是遗传和环境共同作用的结果，倾向于是继发的基因—环境因素相互作用而形成的。
3.It derives from an embryopathy with consequently failure or the nasal process and/or palatal shelves fusion. It can seriously affect the quality of life also and becomes the urgent problem to solve up to now. At present extensive and receptive categorization is divided cleft of lip and palate into NSCLP and SCLP, NSCLP included CLP and CPO.
目前广泛接受的分类是从病原学上将唇腭裂分为非综合征性唇腭裂(nonsyndromic cleft of the lipand／or palate，NSCLP)和综合征性唇腭裂(syndromic cleft of the lipand／or palate，SCLP)，其中非综合征性唇腭裂又可以分为唇裂伴有或不伴有腭裂(cleft lip and palate，CLP)，单纯腭裂(cleft palateonly，CPO)。
4.The concepts of the generalization cleft comodule algebra and thegeneralization H?Galois extension with a nouial basis were due to Masuokaand Doi [MD], they studied the equivalence of them and the dual case. Butthey didn?
Masuoka和Doi[MD]给出了广义cleft余模代数和具有一个正规基的广义H-Galois扩张的概念，他们研究了二者的等价及对偶情形，但没有涉及到Hopfcrossed积或余积。
5.Methods The grade of scarring of UCL after the cleft lip repair in 268 patients was observed and the differences in lip height of noncleft and cleft side, the width of cleft as well as operation approach were studied.
方法 通过观察 2 6 8例单侧唇裂术后瘢痕的程度 ,研究健患侧唇高差、裂隙宽度、术式等因素与瘢痕形成的关系。
6.Objective:To study TGFα and TGFβ3 polymorphisms in patients with nonsyndromic cleft lip with or without cleft palate(NSCLP,CLP or CL)and cleft palate only(CPO).
目的:探讨TGFα基因和TGFβ3基因多态性与国人非综合征型唇腭裂发生的关系。
7.Methods:Fifty patients with secondary deformities after primary repair of the bilatera l cleft lip and bilateral cleft lip and cleft palate from Department of Oral and Maxillofacial Surgery of Xiangya Hospital,Central South University were observe d their 19 secondary deforming contents on the nose,lip and occlusion and jaw. Th ese contents include flattened nasal tip, displacement of the alar cartilages,as ymmetrical nastrils,no nostril sill, short columella.
方法 :选中南大学湘雅医院口腔颌面外科双侧唇裂 /唇腭裂术后继发畸形患者 5 0例作为研究对象 ,观察鼻部、唇部、牙合/颌骨畸形等 19项内容 ,它们分别是 :鼻尖低平、鼻翼塌陷、双侧鼻孔不对称、鼻堤缺失、鼻小柱短小 ;
8.Methods We analyzed 81 cases of congenital craniofacial cleft basically using Tessier craniofacial cleft classification. Furthermore, according to the position of soft tissue or bone, the character and degree of clefts or dysplasia and the results of CT scanning, we subdivided the congenital deformities based on S (skin), T (tissue), and O (OS). Arabic numerals were used to express the degree of the abnormality.
方法用Tessier颅面裂分类的基本方法,对81例先天性颅面裂隙畸形进行分析,再根据畸形发生的部位、性状、CT扫描等临床检查结果,按照受累的范围,选用S(皮肤)、T(皮下组织)、O(颅面骨)等字母组合表示畸形部位和性状,选用阿拉伯数字的大小表示畸形的严重程度,作为Tessier分类的补充。
9.Objective:To explore whether or not the alar cartilage of the unilateral complete cleft lip fetus is hypoplastic by histological comparison to prove the etiology of deformity and provide theory basis for cleft lip surgery.
目的:通过组织学比较,探讨单侧完全性唇裂胎儿鼻翼软骨是否存在发育不足,以揭示其形成机制,为临床唇裂鼻的整复提供理论依据。
10.The TGF-α gene TaqⅠ polymorphism and non-syndromic cleft lip with or without cleft palate
TGF-α基因TaqⅠ RFLPs与国人非综合征性唇腭裂关系的研究
