1.Objective: To evaluate the capability of sodium nitroprusside (SNP) in reversing delayed cerebral vasospasm (DCV) after subarachnoid hemorrhage (SAH), when administered into cisterna magna.
目的了解枕大池注射硝普钠(SNP)对兔蛛网膜下腔出血(SAH)后延迟性脑血管痉挛(DCV)的逆转作用。
2.Conclusion Two times injections of arterial blood into cisterna magna is a reliable method for making DCV after SAH in rats.
结论大鼠枕大池二次注血法是可靠的SAH后迟发性脑血管痉挛模型制作方法。
3.Methods Twenty four Chinese white rabbits were divided into three groups: Kaolin group 12 rabbits, physiological saline group 6 rabbits and shamed operation group 6 rabbits, 25% Kaolin solution was injected into the cisterna magna of animals in the Kaolin goup to produce syringomyelia models, and the other two groups were designed as controls.
方法 取中国白兔 2 4只 ,其中Kaolin组 (12只 )经皮枕大池穿刺注入Kaolin制作动物模型 ,生理盐水组和假手术组 (各 6只 )作对照。
4.Methods Twenty-four of 30 Chinese white rabbits were subjected to injection of 25% kaolin mixed with equal volume (0.6 ml) of cerebrospinal fluid drawn from the cisterna magna under ketamine anesthesia.
方法30只中国白兔随机分为3组。 24只动物经皮枕大池穿刺缓慢抽出0.6ml脑脊液后注入等量25%kaolin,其中12只于当日起给予银杏注射液静脉滴注为银杏组;
5.The transcerebellar (or suboccipitobregmatic) iew allows examination of the mid-brain and posterior fossa; this iew is used for measurement of the transerse cerebellar diameter (TCD) and cisterna magna (CM).
经小脑平面可以检查中脑和颅后窝;该平面用来测量小脑横径(TCD)和颅后窝池(CM)。