1.Methods Using the search terms“bladder neoplasm”,“prognosis”,“p16”or“p21”,the literature on the correlation of p16 gene and p21 gene expression abnor- mality with the prognosis of bladder carcinoma were searched from MEDLINE database,PubMed database, CBMdisc and China Academic Periodical database,and were evaluated by Meta-analysis with Dersimonian- Laird model.
方法以“bladder carcinoma”或“bladder neoplasm”、“prognosis”、“p16”/“p21”和“膀胱癌”、“预后”等为检索词,检索Medline、PubMed、中国生物医学文献及中国学术期刊数据库有关p16基因和p21基因表达异常与膀胱癌预后的文献,应用Meta分析Dersimonian-Laird模型对这些文献进行综合定量评价。
2.Objective To investigate the causes of bladder neck contracture(BNC) after transurethral resection of prostate.
目的对经尿道前列腺电切术(trans urethral resection of prostate,TURP)后发生膀胱颈挛缩(bladder neck contracture,BNC)的原因进行分析,提出预防措施。
3.Results With nephrouretectom y without cuff resection of the bladder,the postoperative occurrence of bladder carcinoma was 54.5%(6/11),being obviously higher than nephroureterectomy with pa rtial bladder resection (23.5%,12/51) or nephroureterectomy with bladder mucosal cuff resection (33.3%,3/9,P0.05).
结果 单发肾盂或输尿管癌行肾盂输尿管切除术 (未切除壁间段输尿管及管口周围部分膀胱 )术后膀胱癌再发率为 5 4.5 % (6 /11) ,明显高于肾盂输尿管膀胱部分切除术 (2 3.5 % ,12 /5 1)和改良膀胱粘膜袖套状切除法肾盂输尿管膀胱部分切除术 (33.3% ,3/9) ,差别有显著性意义 (P
4.After the preparation of bladder acellular matrix graft? the color of the bladder turned into white acellular matrix? but the bladder still kept the bag-like shape.
膀胱无细胞基质移植物的制备过程结束后,膀胱由原来的颜色变为白色的无细胞基质,但仍维持其原来的袋样形态。
5.Conclusions The p33ING1 expression is decreased in bladder TCC tissue; the degree of reduction is associated with pathologic grade and clinical stage of the cancer. It is suggested that the p33ING1 may play an essential role in bladder carcinogenesis and can serve as a marker for prognosis of bladder cancer.
结论p33 ING1在膀胱TCC组织中存在表达缺失,其表达缺失程度与肿瘤病理分级、临床分期及复发相关,可作为观察膀胱TCC复发指标之一。
6.After the turning of the bladder′s lamella, 13 patients were given 20 24 Foley′s tube connecting the pelvis and bladder and nine of them were not subjected to re anastomosis waiting for the pelvis crawling to the bladder as a tunnel.
13例膀胱翻瓣后 ,用2 0～ 2 4Foley尿管连接供肾的肾盂和受者膀胱瓣 ,其中 9例无法实现残留的移植肾输尿管与膀胱瓣无张力的间断缝合 ,只能待移植肾肾盂或上段输尿管沿Foley尿管爬行 ,形成隧道。
7.Methods MAGE-A1,A2,A3,A4 mRNA expression was detected by reverse transcription polymerase chain reaction ( RT-PCR ) in 3 clusters bladder TCC cells and 20 samples of bladder TCC patients(T_1 7 samples,T_2 5 samples,T_3 6 samples,T_4 2 samples,G_1 1 samples,G_2 11 samples,G_3 8 samples). MAGE-A4 protein was detected by immunohistochemistry in 105 samples of bladder TCC patients(T_1 35 samples,T_2 12 samples,T_3 26 samples,T_4 13 samples,G_1 13 samples,G_2 44 samples,G_3 48 samples).
方法采用逆转录聚合酶链反应(RT PCR)技术检测3个膀胱TCC细胞株和20例膀胱TCC患者癌组织(新鲜标本,T1期7例,T2期5例,T3期6例,T4期2例;G11例,G211例,G38例)MAGE A1,A2,A3,A4mRNA表达,免疫组化法检测105例膀胱TCC患者癌组织(石蜡标本,T1期35例,T2期12例,T3期26例,T4期13例,另19例无法确定分期;G113例,G244例,G348例)MAGE A4蛋白的表达。
8.TERT was found in 59(81.9%) of 72 bladder tumor samples,1(7.1%) of 14 adjacent tissues and none of 11 normal bladder tissues, the positive rate of TERT in TCC was signigicantly higher than that in the adjacent tissues and normal bladder tissues(P
TCC组织TERT阳性率为81.9％(59／72)，不同病理分级、临床分期之间无显著性差异(P＞0.05)； 癌旁组织阳性率7.1％(1／14)；
9.Conclusion:The results suggest that pr oapoptosis gene bak are differently expressed in most bladder transitional cel l carcinoma,bak gene may take part in the modulation of apoptosis in bladder tra nsitional cell carcinoma and the expression of bak mRNA is closely related with the degree of bladder transitional cell carcinoma tissue differentiation.
结论 :促凋亡基因bak在大多数膀胱移行细胞癌组织中有不同程度的表达 ,bak基因可能参与膀胱移行细胞癌的凋亡调节 ,并与膀胱移行细胞癌组织的分化有关。
10.Pressure decrease device and pressure discharge valve were separately put between abdominal bladder and capstan bladder in capstan anti-G suit and then the pressure in the abdominal bladder was reduced to approximately 40% of the capstan pressure.
在管式抗荷服的腹囊和两侧管囊间分别装上分压装置和泄压活门,将腹囊内的压力降至管囊内压力的40%左右.
