1.The effects of iontophoretic application of acetylcholine (ACh) and its antagonist atropine on the spontaneous discharge of the neurons in the caudal half of the nucleus paragigantocellularis lateralis (cPGCL) and the influence of atropine on the effects of ACh were observed on 17 anesthetized spontaneously breathing Sprague-Dawley rats.
实验在17只麻醉、自主呼吸的SD大鼠上进行，用多管微电极在旁巨细胞外侧核尾侧半（cPGCL）观察了微电泳乙酰胆碱（ACh）及其桔抗剂Atropine（阿托品）对神经元自发放电的效应及Atropine对ACh效应的影响。
2.2 summarizes the [ 5 S ] GTPS binding on m2AchR protein and m2AchR-Gila fusion protein in the existence of agonist Ach and Cch,or antagonist Atropine and AF-DX116 without GDP.
Table. 2显示，在GDP零浓度时，Ach和Cch使mZAchR一Gila融合蛋白与[”5] GTp，s的结合量增大，而Atropine和AF一Dxll6则使之减小，且明显高于同等条件下mZ AchR蛋白与[3，5] GT巧S的结合量;
3.Microinjection of atropine ( 1.0 ug ) , a muscarinic receptor blocker , promoted SWS and abolished the effect of ACh .
海马内微量注射M胆碱受体阻断剂阿托品(atropine，1.0μg)使SWS增多，睡眠加深，并可完全阻断ACh的效应。
4.The present study showed that GH secretion was increased during exercise and the elevated GH level could be inhibited by atropine in normal subjects, while in patients with active acromegaly the high basal GH levels could be inhibited neither by 100g of glucose loading nor by 0.6 mg atropine. The blood sugar concentrations remained unchanged during atropine test.
本研究证实,在正常人,蹬车运动试验可激发GH分泌增加,而口服阿托品又可抑制由运动激发的GH分泌; 活动性肢端肥大症患者,高分泌的GH水平不受100g葡萄糖、也不受0.6mg阿托品的抑制,且在阿托品试验中,血糖处于稳定状态。
5.Atropine 0.lmg/kg icv stimulated respiration and slowed heart rate. When DHE was combined with atropine(0.05-0.1 mg/kg icv) , the inhibition of respiration was abolished but the slow heart rate persisted.
侧脑室注射阿托品0.1mg/kg使兔呼吸加快和心率减慢,两药合用,阿托品可拮抗DHE呼吸抑制作用,但不能拮抗其心率减慢。
6.Part two : Comparing with atropine model group, WCS markedly promoted gastic emptying when gastric motility was delayed by atropine in mice(P
模型组胃窦组织生长抑素阳性细胞明显高于空白对照组、胃肠舒液灌胃组及胃肠舒液结肠深部保留灌肠组，有显著差异(P
7.In order to evaluate the effects of Atropine on atrioventricular conduction intervals in patients with atrioventricular Block(AVB), an experiment on 10 patients with AVB was conducted using electrophysiology techniques, and the changes of the conduction intervals in or between atrium and ventricle were individually examined before and after Atropine administration The results show that there are not obvious changes in PA or HV interval (P>0 05);
为了评价阿托品对房室传导阻滞（AVB）患者各传导间期的影响，我们采用现代电生理检查技术对10例患者应用阿托品前后各房室传导间期的变化作了对比分析，结果发现PA间期及HV间期的变化无统计学意义（P＞0．05），AH间期变化有显著性差异（P＜0．01）。
8.Objective: Our aim was to compare the clinical effects of oral premedicant of mixture of midazolam, ketamine and atropine with muscle injection of valium and atropine in children.
目的:比较小儿术前口服咪唑安定氯胺酮阿托品混合液与常规方法肌注安定阿托品的临床效果。
9.To assess the medicinal value of cultural Anisodus tanguticus,the contents of four bioactive tropane alkaloids,anisodine,anisodamine,scopolamine and atropine,in cultural and wild materials were determined by the HPLC method.The results showed that content of each alkaloid in the aboveground parts of cultural and wild samples was lower than that in roots,and this explained why it was not the whole plant but the root that was used as medicinal materials.The content of each alkaloid in the roots of one-year cultural material was lower than that in the two-year plants.The discrepancy of the total of four alkaloids between one-year and wild plants is not significant.Moreover,the total of four alkaloids,and the contents of anisodine,scopolamine,and atropine in two-year plants were higher than those in wild plant.Thus there is medicinal value in the cultivated A.tanguticus as well as wild A.tanguticus,especially in the two-year cultural A.tanguticus.
为了评估人工栽培山莨菪的药用价值,采用高效液相色谱技术对人工栽培和野生山莨菪的地上部分和根中具有生物活性的4种托烷类生物碱:樟柳碱、山莨菪碱、东莨菪碱和阿托品的含量进行了测定.结果表明无论是人工栽培还是野生植物,地上部分中4种生物碱含量均远低于根,这解释了人们为什么用山莨菪的根而不是整株入药.在栽培植物的根中,一年生山莨菪中各生物碱含量均小于二年生山莨菪,其根中4种生物碱总量与野生根相比差异不是很明显;二年生山莨菪根中,4种生物碱总量以及樟柳碱、东莨菪碱和阿托品含量均比野生的高.这说明人工栽培的山莨菪,尤其是二年生山莨菪,同野生山莨菪一样具有一定的药用价值.
10.The results were as follows: (1) The propulsive distance of charcoal meal was significantly reduced in a dose-dependent manner after ICV injections of TRH (1μg/10μl, 5μg/10μl or 10μg/10μl) (P
侧脑室内注射0.5,1,5和10μg TRH能显著减弱胃肠推进运动,且这种效应呈剂量反应关系。
