1.Relationship between loss of heterozygosity of microsatellite on DCC gene and prognosis of colorectal adenocarcinoma
Relationship between loss of heterozygosity of microsatellite on DCC gene and prognosis of colorectal adenocarcinoma
2.According to the locations of the tumors, it can be named as distal end GC and gastric cardia adenocarcinoma (GCA).
根据肿瘤的发生部位，GC可以分为远端胃癌和贲门癌(gastric cardia adenocarcinoma，GCA)。
3.Methods According to the K-ras point mutant type (CGT, GTT and GAT) in pancreatic adenocarcinoma, three kinds of sequence special primer (SSP) for ploymerase chain reaction were designed, where K-ras gene fragment was amplified from frozen or paraffin embedded pancreatic adenocarcinoma tissues, fine needle aspiration sample from pancreatic adenocarcinoma and pancreatic juice of patients with pancreatic carcinoma. K-ras point mutation of the amplified product was detected by gel electrophoresis.
方法 采用针对K-ras基因点突变方式（CGT、GAT、GTT）设计的顺序特异性引物（SSP）,先后对胰腺癌石蜡包埋组织、冰冻新鲜组织、细针穿刺组织及胰液进行多聚酶链反应（PCR）,扩增产物借助常规电泳和染色检测有无K-ras基因突变及突变方式。
4.on the basis of this. We attempt to ovaluate the curative effect and prognosis. We also proposed that most of these three kind of X—ray classified gastric carcinomas ulcer type, mass type and infiltration type are tubular adenocarcinoma and low differentiation adenocarcinoma in histology, and they adept to preoperative radiotherapy.
还提出了胃癌的溃疡型、肿块型和浸润型三种大体X线类型,其组织学以管状腺癌、低分化腺癌居多数,适合手术前放射治疗。
5.[Objective]: To investigate the effect of DFF45/ICAD and P57KIP2 protein in the carcinogenesis and progression of humam colorectal adenocarcinoma and to identify their correlations with the invasion and metastasis of colorectal adenocarcinoma.
[目的]：研究DFF45／ICAD、P57~(KIP2)在人大肠腺癌发生发展过程中的作用，并探讨其与大肠腺癌侵袭和转移的关系。
6.(4) Elevated levels of IL-10 were found in SCLC group with respect to NSCLC. IL-12 from PBMC and AM were lower than that of adenocarcinoma, adenocarcinoma and squamous carcinoma separately.
(4) SCLC组IL-10水平显著高于腺癌组及鳞癌组，而PBMC分泌的IL-12水平低于腺癌组，AM分泌的IL-12水平低于腺癌组及鳞癌组。
8.(3) The expresson of p53 had a positive con-relation with differentiated degree oflung adenocarcinoma, qualitative analysis p53 (- 7+) p=O. OOS; quantitativeanalysis P53(PU): p=0.035. It suggested that the expression of p53 in well-differentiated adenocarcinoma was lower than the moderately- and lowly-differentiated ones.
（3）不同分化程度肺腺癌之间p53的表达具有显著性差异[定性表达p53（-/+）的p=0.005；定量表达p53（PU）的p＝0.035]，提示高分化肺腺癌p53的表达低于中、低分化肺腺癌。
9.Conclusion The effect of VEGF and COX-2 expression to prognosis of lung adenocarcinoma may be an index that can be used to estimate prognosis of lung adenocarcinoma and constitute logical Rx.
结论VEGF、COX-2表达对肺腺癌预后有一定的影响,可作为估计肺腺癌预后、指导制定合理治疗方案的指标。
10.During the experimental period(488 days)8 animals has developed lungtun ors which consisted of 3 cases of bronchilo-alveolar cell carcinomcand 5 cases of poorly differentiated adenocarcinoma The experimental results obtained the histogenetic origin of peripheral adenocarcinoma of lung in hamsterwas demonstrated to be the clara cells as well as the alveolar type Ⅱ cells.
其中细支气管肺泡癌3例,低分化腺癌5例。 实验结果证明周边型肺腺癌可来源于Clara细胞及Ⅱ型肺泡上皮细胞。
